A peripheral blood stem cell transplant is a method which involves ‘mobilising’ stem cells from your bone marrow by administering white blood cell growth factors, followed by ‘collecting’ these cells from your blood stream. Stem cells generally need to be collected using a cell-separator on three consecutive days in order to obtain enough stem cells for a transplant.
The stem cells are transfused back into your body after you receive radiation therapy or high dose chemotherapy. This reduces the toxic effects of radiation therapy and chemotherapy on the bone marrow and blood counts. This means high doses of chemotherapy are able to be given safely.