Myelodysplasia affects the growth and development of healthy blood cell formation in your bone marrow. You may also hear it referred to as myelodysplastic syndrome.
Myelodysplasia impacts the production of blood cells and restricts their development. Over time there are more defective blood cells than healthy blood cells, which can cause other symptoms and health conditions such as anaemia.
There are many different kinds of myelodysplasia classified according to the morphology (appearance) and cytogenetic changes of the bone marrow cells. These include:
- Refractory anaemia
- Refractory anaemia with ringed sideroblasts
- Refractory cytopenia with multilineage dysphasia
- Refractory cytopenia with multilineage dysphasia and ringed sideroblasts
- Myelodysplastic syndrome with del(5q) chromosome
- Myelodysplastic syndrome with excess blasts
- Mixed myelodysplastic/myeloproliferative neoplasms
In some cases myelodysplasia can progress to leukaemia.